Since QNX Neutrino is a protected-mode 32-bit operating system, many limiting design considerations won't apply (particularly on the x86 platform, which is steeped in DOS and 8088 legacy concerns). By noting the various "do's" and "don'ts" given in this appendix, you'll be able to design and build an embedded system tailored for QNX Neutrino.
You may also be able to realize certain savings, in terms of design time, hardware costs, and software customization effort.